Summary of Dopamine Nation by Anna Lembke

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  • Post last modified:February 3, 2024

Part II: Self-Binding

Chapter 4: Dopamine Fasting

People that need to get off their drugs can use the framework DOPAMINE to do so.

  • D for data: what are you using, and how many times a day?
  • O for objective: why do you take this product? To cope? To feel pleasure? To escape pain?
  • P for problems: what’s the downside of consuming the drug?
  • A for abstinence: stop for a month to restore homeostasis.
  • M for mindfulness: go through the pain of withdrawal. Do not worry, you will feel better afterward.
  • I for insight: what happens when you abstain from your drug?
  • N for next step: what do you want to do after abstaining for a month? Keep yourself clean or…go back? Usually, people want to keep using the drug, but not to the same extent.
  • E for experiment: Figure out what works and what doesn’t so you don’t go back to being miserably addicted. Most of the time, most people need to practice complete abstinence.

Now, what do you do when you get addicted to something you must use like a smartphone, or food?


Chapter 5: Space, Time, and Meaning

Self-binding is the action of putting up barriers to stop yourself from taking your drugs. It’s not about self-discipline. It’s about recognizing that self-discipline has some limits.

There are three types:

Physical strategies

Get rid of your TV, block porn sites, or move to another place.

Some people take naltrexone, a medicine that blocks the opioid receptors in the brain. Another is disulfiram, which makes people sick when they drink alcohol, thereby changing the association in the mind.

It’s important to treat the underlying cause of the addiction. People with gastric banding often become alcoholics since they can no longer cope with food.

Chronological Strategies

These entail consuming the drug only at certain times: eg: the weekend; no more till Christmas; only until my birthday, etc.

Studies suggest this works better than if you have unlimited access at every hour.

Something funny: addicted people are less willing to wait for anything in general and less likely to delay gratification than non-addicts. This is because instantaneous rewards trigger more dopamine than delayed ones – and they’re hooked on dopamine.

In today’s dopamine-rich ecosystem, we’ve all become primed for immediate gratification.

-> Google gives instant results, Amazon gives instant delivery, and Netflix provides instant entertainment.

Kids growing up in poverty are more likely to choose instantaneous gratification than kids growing up in a wealthy environment, hence priming the former for addictions.

Furthermore, we work less today than before, which means we are more bored, which means we are more prone to dopamine activities.

And while working less (or getting bored) increases your chances to become addicted, being addicted compels you to work less.

The vicious circle of addiction and laziness.
The vicious circle of addiction and laziness.

Categorical strategies

It’s about cutting yourself off from the cues that trigger the addiction.


Chapter 6: A Broken Balance?

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Sometimes, the balance is naturally broken.

There are two problems with pain-relieving psychiatric drugs.

  1. They usually become addictive.
  2. We don’t know exactly how they work. What if they make the psychiatric symptoms worse?

What if taking psychotropic drugs is causing us to lose some essential aspect of our humanity?

Most people on psychiatric drugs have been relieved in the short-term, but were incapable of experiencing powerful emotions in the long term.

In medicating ourselves to adapt to the world, what kind of world are we settling for?

By treating people for pain, we’re making them tolerant of intolerable situations.

Furthermore, without pain for anything…we lack the motivation to do things.


Part III: The Pursuit of Pain

Chapter 7: Pressing on the Pain Side

The author tells the story of one of her patients who solved his cocaine craving by taking cold showers.

He noticed that not only this decreased his desire for the drug, but it also made him happy – like taking the drug.

A team of scientists showed that cold water exposure increased dopamine concentrations by 250%, and norepinephrine increased by 530%. These last up to one hour after exposure to the stimulus.

-> doing painful things eventually makes you happy!

By pressing on the pain side of the balance first, the brain compensates by triggering pleasure.

Pain leads to pleasure by triggering the body’s own regulating homeostatic mechanisms.

The pleasure we feel is just the response to pain.

With intermittent exposure to pain, our natural hedonic set point gets weighted to the side of pleasure, such that we become less vulnerable to pain and more able to feel pleasure over time.

Something Socrates had already found out thousands of years ago!

The Science of Hormesis

Hormesis is the science that studies the effect of introducing small amounts of pain like cold, heat, food restriction, or exercise.

The idea is that a small painful stimulus will make living things stronger (antifragility) but too much of it could of course break them.

Among Japanese citizens living outside the epicenter of the 1945 nuclear attack, those with low-dose radiation exposure may have shown marginally longer lifespans and decreased rates of cancer compared to un-irradiated individuals.

Physical exercise, for example, is immediately toxic to cells. Yet all in all, it strongly benefits your body and helps you live longer.

It also increases neurotransmitters making you in a good mood, such as:

  • dopamine
  • serotonin
  • norepinephrine
  • epinephrine
  • endocannabinoid,
  • endogenous opioid peptides (endorphins)

Exercise also contributes to the birth of new neurons and reduces the likelihood of getting addicted to drugs.

Dopamine has been shown to be associated with the realization of a desire. Of course when dopamine is accessible by just touching a button on a phone…then we stop to be compelled to go get what we want since it automatically arrives (Eg: Ubereat).

On the other hand, pursuing pain instead of pleasure is hard, countercultural, and counter-intuitive too.

Pain to Treat Pain

Of two pains occurring together, not in the same part of the body, the stronger weakens the other.

Hippocrates

Pain has been used to treat pain for more than 2000 years. Pain has been used to treat pain for more than 2000 years.

These therapies declined in the 20th century with the discovery of drug therapy.

Yet the methods of the past were not necessarily wrong. A team of scientists found out that the subjective experience of pain caused by an initial painful stimulus decreased with the application of a second painful stimulus.

This may also be why and how acupuncture works: it triggers pain in certain parts of the body which the body automatically takes care of.

Likewise, patients that have phobias learn to get rid of them by exposing themselves to the thing they’re scared of.

Related to this, Alex Honnold, the guy who climbed the El Capitan without ropes, has a higher fear tolerance than most people, likely due to repeated training.

Addicted to Pain

Now, some people go completely the other way and get addicted to the pain itself.

The high they get after cold water or exercise is so good that they increase and increase the pain as the bigger the pain, the bigger the high.

This is the case for the running wheels of lab mice: they become drugs (a lab rat will voluntarily use a running wheel in the wild).

The running wheel is to a rodent what extreme sports are to people. Stress has even been shown to be associated with dopamine release, in some cases.

Skydivers in fact have a higher risk of anhedonia than other people, because the high is addictive.

-> too much pain can increase the risk to become addicted to the pain!


Chapter 8: Radical Honesty

Children begin to lie as early as two years old.

The smarter the kid, the more likely they are to lie, and the better they are at it.

We’re wired to lie.

Why? Because telling the truth hurts. And lie, because it is first pleasurable, can quickly become addictive.

Addicted people are also often pathological liars. They even lie about stuff that doesn’t make sense to lie about (breakfast menu).

Radical honesty is essential for the following reasons:

  1. Radical honesty promotes awareness of our actions: most addicts are in denial, likely due to a disconnect between the reward pathway and the part that narrates events in their brains.
  2. It creates intimate connections with other people: they come closer to you as they identify and relate to your own weaknesses.
  3. It holds us accountable to our present and future selves.
  4. It’s contagious and can prevent other addictions.

When Odysseus decided to listen to the sirens, tied to the mast, he did not only do it to hear them. He also knew that the sirens would die if anyone that heard them lived to tell about it.

-> telling what happened enables us to master it.

A team of scientists discovered that stimulating the prefrontal cortex with electricity made people more honest.

It may also be the other way around: telling the truth stimulates the prefrontal cortex -> telling the truth changes us.

Not only does it change us, but like pain, it’s also addictive when it enables the strengthening of relationships with people.

While truth-telling promotes human attachment, compulsive overconsumption of high-dopamine goods is the antithesis of human attachment. Consuming leads to isolation and indifference, as the drug comes to replace the reward obtained from being in relationship with others.

Experiments show that a free rat will instinctively work to free another rat trapped inside a plastic bottle. But once that free rat has been allowed to self-administer heroin, it is no longer interested in helping out the caged rat, presumably too caught up in an opioid haze to care about a fellow member of its species.

image 12
The more addicted you are, the less interested you are to be with other people.

Some people may even get addicted to their addiction stories because they trigger reactions in the audience to which they get addicted. It’s called drunkalogues.

Telling the truth also helps you get better. People that tell their lives from a victim’s point of view are often unwell (and remain so). People telling their stories and taking responsibility usually get better.

The self-victimization societal trend is a problem.

Even when people have been victimized, if the narrative never moves beyond victimhood, it’s difficult for healing to occur.

A truthful autobiographical narrative further allows us to be more authentic, spontaneous, and free in the moment.

Another consequence of lying is the false self. A false self is created when the real self is assaulted by unrealistic demands and expectations. Social media, for example, enabled us to create a false self by portraying a reality that just isn’t so.

The problem is that the creation of a false self makes us feel fake, detached, and unreal.

The only antidote is the real self.

Finally, truth-telling helps with having an abundance mindset.

Children that know of broken promises, or that were lied to and subsequently discovered it, grow up in a world where they don’t get honesty or the things they were told they could expect. They grow up in a dangerous world that cannot be trusted.

We go into competitive survival mode and favor short-term gains over long-term ones, independent of actual material wealth. This is a scarcity mindset.

Why do we have a scarcity mindset in the Western world where there is an abundance of everything?

Because too much dopamine makes us crave things (more dopamine), hence conveying the idea that “there isn’t enough”.

One of the ways to find abundance everywhere is to work on a purpose bigger than ourselves and be connected to people.

And this requires honesty.


Chapter: 9 Prosocial Shame

Shame is an emotion that makes us feel guilty about ourselves as people, while guilt makes us feel guilty about our actions.

Overconsumption can lead to shame, which itself can both encourage or repress the “shameful” behavior.

Indeed, there are two types of shame:

  1. Destructive shame: other people shaming us. The pattern is: Overconsumption -> shame -> lying -> isolation -> overconsumption, etc.
  2. Prosocial shame: Overconsumption -> shame -> radical honesty -> acceptance and empathy -> increased belonging and decreased consumption.

Truth (and discipline) is once again, extremely important.

When we’re accountable to ourselves, we’re able to hold others accountable.

Stricter churches achieve a larger following and are generally more successful than freewheeling ones because they ferret out free riders and offer more robust club goods.

Social media propels our tendency toward self-shame by inviting so much invidious distinction. We’re now comparing ourselves not just to our classmates, neighbors, and coworkers, but to the whole world, making it all too easy to convince ourselves that we should have done more, or gotten more, or just lived differently.


Conclusion: Lessons of the Balance

What if instead of taking drugs to escape the painful aspects of life, we immersed ourselves in these painful aspects?

Stop running from whatever you’re escaping from. Turn away.

And face it.

For more summaries, head to auresnotes.com.

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